Effect of genistein on the development and progression of prostate cancer

Partha Banerjee

Anti-proliferative properties of genistein (phytoestrogen) in prostate and other cancers have been studied extensively. However, the identification of genistein targets that may mediate its chemopreventive effects in vivo requires further elucidation. Using the TRAMP (Transgenic Adenocarcinoma of MouseProstate) model and human prostate cancer cell lines, we are investigating the molecular mechanisms by which genistein regulates growth of prostate cancer cells.